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Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis
This open-label, randomized, controlled trial involved couples in which a woman had bacterial vaginosis and was in a monogamous relationship with a male partner showed that the addition of combined oral and topical antimicrobial therapy for male partners to treatment of women for bacterial vaginosis resulted in a lower rate of recurrence of bacterial vaginosis within 12 weeks than standard care. Full Access: NEJM
Current Dengue Outbreak
In the United States, public health authorities in Puerto Rico and us Virgin Islands have declared dengue outbreaks. Locally acquired dengue cases have been detected in Florida, Texas, Hawaii, Arizona, and California. Large outbreaks of dengue can increase the risk the number of dengue cases in US travelers. Because of the increased number of travel-associated cases and because the types of mosquitoes that spread dengue are present in some areas of the United States, small outbreaks might occur. Full Access: CDC
Report Ranks U.S. Cities for Challenges Living With Allergies
More than 100 million people in the United States live with various types of allergies every year.1,2 Many of them have seasonal pollen allergies. The Asthma and Allergy Foundation of America’s (AAFA) yearly Allergy Capitals report explores how challenging it is to live with seasonal allergies in the top 100 U.S. cities. Full Access: AAFA
Tailored Adherence Incentives for Childhood Asthma Medications – A Randomized Clinical Trial
In this randomized clinical trial of 99 school-aged, adherence to inhaled preventive medications was temporarily boosted by a financial incentive-enhanced mobile health intervention, though there was no evidence of enduring behavior change. Full Access: JAMA
Probiotics and Fever Duration in Children with Upper Respiratory Tract Infections – A Randomized Clinical Trial
In this randomized clinical trial involving 128 children with upper respiratory tract infections (URTIs) URTIs, the probiotic mixture shortened the duration of a fever by 2 days, a statistically significant difference compared with placebo. The findings suggest that probiotics are helpful in the treatment of pediatric URTIs. Full Access: JAMA
Infection Prevention and Control Measures for Multidrug-Resistant Organisms: A Systematic Review and Network Meta-Analysis
PubMed, Embase, MEDLINE, Cochrane Library, and CINAHL were searched to assess The effectiveness of infection prevention and control measures combating multidrug-resistant organisms (MDROs). Researchers found that the optimal interventions to reduce the acquisition, infection, and colonization of MDROs vary within the hospital setting. These interventions must be tailored according to the specific intervention implemented and the type of resistant strain involved. Full Access: Springer
Removing Ineffective Drugs from the Market – Implications for Oral Phenylephrine and Beyond
When evidence shows that a long-approved medication is ineffective, should it remain available if there are no concerns for harm? The recent case of oral phenylephrine opens this discussion with multiple repercussions. Full Access: JAMA
Non-invasive monitoring of humoral immune responses in men with acute Chlamydia trachomatis urethral infection using first-catch urine
Researchers investigated the relationship between Chlamydia trachomatis (CT) load and anti-chlamydial antibody using first-catch urine from men with nongonococcal urethritis. Genotype-specific differences in CT load, clarify that partial immunity associated with repeat infections is not antibody-mediated, and demonstrate a method to monitor humoral immune responses to CT in men using non-invasively collected urine. Full Access: Journal of Infectious Disease
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