2024 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations
This latest summary addresses the most recent published resuscitation evidence reviewed by the International Liaison Committee on Resuscitation task force science experts. In addition, the task forces list priority knowledge gaps for further research. Full Access: AHA
Wound Characteristics Among Patients Exposed to Xylazine
In this case series of patients with confirmed xylazine exposure, wounds were commonly located on extensor surfaces of the extremities, frequently had devitalized wound beds and were more likely to have larger and necrotic wound beds the longer wounds had persisted. Full Access: JAMA
Cephalosporins for Outpatient Pyelonephritis in the Emergency Department: COPY-ED Study
This was a multicenter, retrospective, observational cohort study of 11 geographically diverse U.S. Emergency Departments. Researchers found that oral cephalosporins were associated with similar treatment failure rates compared with Infectious Diseases Society of America guideline-endorsed treatments for the treatment of pyelonephritis in ED patients discharged home. Full Access: Annals of Emergency Medicine
Comparative Effects of Drug Interventions for the Acute Management of Migraine Episodes in Adults: Systematic Review and Network Meta-Analysis
In these randomized controlled trials, eletriptan, rizatriptan, sumatriptan and zolmitriptan had the best profiles, and they were more efficacious than the recently marketed drugs lasmiditan, rimegepant and ubrogepant. Although cost effectiveness analyses are warranted, and careful consideration should be given to patients with a high-risk cardiovascular profile, the most effective triptans should be considered as preferred acute treatment for migraine and included in the WHO List of Essential Medicines to promote global accessibility and uniform standards of care. Full Access: BMJ
