Urgent Updates | October 13, 2022

LONG-TERM HOUSEHOLD CONTAMINATION WITH MONKEYPOX VIRUS INVESTIGATED
An investigation by CDC and state health authorities in Utah found monkeypox virus on many frequently used household surfaces, blankets, furniture, and other objects in a home where residents had been isolating for weeks. They recommended that individuals living with or visiting an infected person’s home wear a mask, avoid touching potentially contaminated surfaces, wash their hands, and avoid sharing utensils, clothing, bedding, or towels.
Full Access: JAMA

NOROVIRUS OUTBREAKS REPORTED THROUGH NOROSTAT — 12 STATES, AUGUST 2012–JULY 2022
CDC showed there were nearly triple the outbreaks from August 2021 through July 2022 compared with the same time period in 2020-2021. Of the outbreaks in 2021-2022, 82% were due to person-to-person spread, with the majority — 59% — occurring in long-term care facilities. After a slump in reported norovirus outbreaks during the pandemic, numbers have rebounded to pre-pandemic levels as COVID-19 mitigation measures have eased around the country, CDC researchers reported Thursday.
Full Access: CDC

AAP GUIDANCE HELPS DISTINGUISH BLEEDING DISORDERS FROM ABUSE
On Sept. 19 the American Academy of Pediatrics published two reports — a clinical report and a technical report — in the October 2022 issue of Pediatrics on evaluating for bleeding disorders when child abuse is suspected. The reports emphasize that laboratory testing of bleeding cannot always rule out abuse, just as a history of trauma (accidental or nonaccidental) may not rule out a bleeding disorder or other medical condition. The decision on whether to evaluate for a bleeding disorder may be made case by case.
Full Access: AAP

STATE STRATEGIES FOR PREVENTING PREGNANCY-RELATED DEATHS: A GUIDE FOR MOVING MATERNAL MORTALITY REVIEW COMMITTEE DATA TO ACTION
About four in five pregnancy-related deaths that occurred in the United States from 2017 to 2019 were preventable, according to the CDC. Maternal mortality review committees (MMRCs) across the nation are using shared processes and terminology to understand how to prevent maternal mortality presents translating data into action as an iterative four-step process, with each step approached through an equity lens and supported by continuous monitoring and review.
Full Access: CDC

SARS-COV-2 INFECTION DRIVES AN INFLAMMATORY RESPONSE IN HUMAN ADIPOSE TISSUE THROUGH INFECTION OF ADIPOCYTES AND MACROPHAGES
The aim of this study was to determine if human adipose tissue is permissive to SARS-CoV-2 infection. Researchers obtained adipose tissue from individuals after consent and exposed these samples to SARS-CoV-2 in vitro and measured viral entry, replication, and inflammatory. This in-depth analysis of adipose tissue susceptibility and inflammatory responses to SARS-CoV-2 infection suggests that adipose tissue could serve as a potential reservoir for SARS-CoV-2 and potentiator of regional or systemic inflammation, possibly contributing to clinical disease in individuals suffering from COVID-19.
Full Access: Science