Increased Risk of Dengue Virus Infections in the United States
The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to notify healthcare clinicians, public health authorities and the public of an increased risk of dengue virus (DENV) infections in the U.S. in 2024. A few highlights of their recommendations: (1) increased suspicion of dengue among people with fever who have been in areas with frequent or continuous dengue transmission within 14 days before illness onset; (2) order appropriate diagnostic tests for acute DENV infection: reverse transcription polymerase chain reaction [RT-PCR] and IgM antibody tests, or non-structural protein 1 [NS1] antigen tests and IgM antibody tests. Full Access: CDC
Cranberry Juice Good for Preventing Urinary Tract Infection
This systematic review and network meta-analysis of 20 trials involving 3,091 children and adults at risk for UTIs. Consumers of cranberry juice had a 54% lower rate of UTIs compared with participants who had no treatment, and a 27% lower rate compared with those who took a liquid placebo, investigators reported in European Urology Focus. Full Access: Renal and Urology News
Long-Acting Cabotegravir Appears Safe in Pregnancy
HIV pre-exposure prophylaxis (PrEP) with long-acting injectable cabotegravir (CAB-LA; Apretude) appeared safe during pregnancy among cisgender women, according to an analysis of the HPTN 084 open-label extension trial. Full Access: Medpage
Acute Gastroenteritis Linked to Increased Odds for Post-infection IBS, Functional Dyspepsia
Patients with acute gastroenteritis had up to fourfold increased odds for developing post-infection irritable bowel syndrome or functional dyspepsia, with a higher risk associated with proinflammatory microbes and SARS-CoV-2. The prevalence of post-infection IBS and functional dyspepsia was 14.5% and 12.7%, respectively, after acute gastroenteritis. IBS persisted in 52.3% of patients at 1 to 4 years follow-up and in 39.5% at five years. Full access: Helio
Heat-Related Illness in Athletes
Heat is a well-studied stressor to athletic performance. Serious exertional heat illness (EHI) at its extreme causes exertional heat stroke (EHS), with a core temperature generally greater than 40 °C (104 °F) and altered mental status (confusion, delirium, stupor, or unconsciousness), which can cause organ failure and death. Full Access: JAMA
