FDA panel supports approval of two-drug asthma inhaler for adults, split on adolescents
The fixed-dose combination of budesonide and albuterol sulfate metered dose inhaler (Avillion, AstraZeneca), or BDA, has been submitted to FDA for review for the as-needed treatment or prevention of bronchoconstriction and to prevent asthma exacerbations among patients with asthma aged 4 years and older. The FDA’s Pulmonary-Allergy Drug Advisory Committee voted 16-1 in favor of approving the fixed-dose combination of budesonide and albuterol sulfate metered dose inhaler for patients with asthma aged 18 years and older.
Full Access: Helio
The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study
In this multicenter, prospective, observational birth cohort study, researchers found RSV causes 1 in 50 deaths in children under Age 5. RSV-associated acute respiratory infection causes substantial morbidity, leading to the hospitalization of one in every 56 healthy term-born infants in high-income settings. Immunization of pregnant women or healthy term-born infants during their first winter season could have a major effect on the health-care burden caused by RSV infections.
Full Access: The Lancet
Factors Associated with Dermatologic Follow-up vs Emergency Department Return in Patients With Hidradenitis Suppurativa After an Initial Emergency Department Visit
In this cohort study of 20 269 patients with HS presenting to the ED for their HS or related proxy, ED return was high and dermatology outpatient follow-up was low. Opioid prescription at the index ED visit and Medicaid status were important factors associated with increased ED return and, in contrast, decreased dermatology outpatient follow-up for HS. Emergency department (ED) readmission was more common than dermatology follow-up among patients with hidradenitis suppurativa (HS) within 30 and 180 days of initially presenting to the ED, with patients with Medicaid coverage and those who had an opioid prescribed were more likely to return.
Full Access: JAMA