Urgent Updates | May 30, 2024

Burden of Disease Scenarios For 204 Countries and Territories, 2022–2050: A Forecasting Analysis for The Global Burden Of Disease Study 2021

Mostly due to growth and ageing of populations, the number of deaths and DALYs due to all causes combined will generally increase. Researchers predict Life expectancy around the world is expected to increase by nearly 5 years in men and more than 4 years in women during the next three decades. By constructing alternative future scenarios wherein certain risk exposures are eliminated by 2050, we have shown that opportunities exist to substantially improve health outcomes in the future through concerted efforts to prevent exposure to well established risk factors and to expand access to key health interventions. Full Access: The Lancet

Electrocardiographic Predictors of Left Ventricular Scar in Athletes with Right Bundle Branch Block Premature Ventricular Beats

Right bundle branch block (RBBB) morphology non-sustained ventricular arrhythmias (VAs) have been associated with the presence of non-ischemic left ventricular scar (NLVS) in athletes. The aim of this cross-sectional study was to identify clinical and electrocardiogram (ECG) predictors of the presence of NLVS in athletes with RBBB VAs. Full Access: European Journal of Preventive Cardiology

FDA Clears AI Algorithm for Detection of Worsening HF

The FDA cleared an AI algorithm for the detection of worsening HF and imminent hospitalization. The algorithm sends an alert to the patient’s care team when risk scores reach an established threshold. The algorithm (SignalHF) was trained and validated using the Health Data Hub, one of the largest CVD databases in the world, and datasets from the company’s AI-based remote monitoring platform. Full Access: Helio

Efficacy of Dequalinium Chloride vs Metronidazole for the Treatment of Bacterial Vaginosis

In this randomized clinical trial of 147 premenopausal women with bacterial vaginosis, the difference in the clinical cure rate between dequalinium chloride and metronidazole was −0.5. The results are statistically significant and indicate the noninferiority of dequalinium chloride. These findings indicate that treatment with dequalinium chloride is as effective as oral metronidazole for curing bacterial vaginosis, thus showing similar efficacy to first-line antibiotic treatments. Full Access: JAMA