Urgent Updates | May 11


Pediatric Lyme Disease: Systematic Assessment of Post-Treatment Symptoms and Quality of Life

This study characterized long-term outcomes of pediatric patients with Lyme disease and evaluated the case definition of post-treatment Lyme disease (PTLD) syndrome. Most pediatric patients treated for all stages of Lyme disease reported full resolution of symptoms within 6 months. 22% of pediatric patients reported one or more symptom persisting >6 months, 9% with and 13% without accompanying functional impairment. Full Access: Nature

FDA Approves First RSV Vaccine

On May 3rd, U.S. Food and Drug Administration approved Arexvy, the first respiratory syncytial virus (RSV) vaccine approved for use in the United States. Arexvy is approved for the prevention of lower respiratory tract disease caused by RSV in individuals 60 years of age and older. The safety and effectiveness of Arexvy is based on the FDA’s analysis of data from an ongoing, randomized, placebo-controlled clinical study conducted in the U.S. and internationally. Full Access: FDA

Effects Of Patient Beliefs Regarding the Need for Antibiotics And Prescribing Outcomes On Patient Satisfaction In Urgent-Care Settings

Researchers studied how patient beliefs regarding the need for antibiotics, as measured by expectation scores, and antibiotic prescribing outcome affect patient satisfaction using data from 2,710 urgent-care visits. In this study, patient beliefs regarding the need for antibiotics were significantly associated with patient satisfaction only among patients with moderate-to-high expectation scores for antibiotics. Researchers suggest that decreasing urgent-care patient expectations and beliefs regarding the need for antibiotics may decrease unnecessary prescriptions without negatively impacting patient satisfaction. Full Access: SHEA

Trial of a multi-faceted intervention to improve management of antibiotics for children presenting with respiratory tract infections

Amongst children aged 0-9 years presenting to a general practice clinic with respiratory infections, an intervention encompassing risk stratification and caregiver education did not decrease antibiotic dispensing rates or increase hospital admission rates. Full Access: 2minutemedicine