Urgent Updates | March 23

Women lose more quality-adjusted life-years than men because of STDs
Estimates of lifetime quality-adjusted life-years lost due to gonorrhea, chlamydia and trichomoniasis were substantially higher among women than among men in 2018. Through this analysis, they found that the estimated total discounted lifetime QALYs lost due to infections in 2018 were highest for chlamydia (1,541 QALYs lost among men and 111,872 QALYs lost among women), followed by gonorrhea (989 QALYs lost among men and 12,112 among women) and lowest for trichomoniasis (386 among men and 4,576 among women).
Full Access: Helio

US FDA approves Pfizer’s nasal spray for migraine
The U.S. Food and Drug Administration approved Pfizer Inc’s nasal spray Zavzpret for migraine treatment, giving patients access to a potentially fast-acting pain-relief option for headaches.
Full Access: Reuters 

Nonopioid pharmacological management of acute low back pain: A level I of evidence systematic review
All the randomized controlled trials investigating the efficacy of myorelaxants, nonsteroidal anti-inflammatory drugs (NSAIDs), and paracetamol for acute lower back pain (LBP). Myorelaxants and NSAIDs were effective in reducing pain and disability in acute LBP at approximately one week. The combination of NSAIDs and paracetamol was associated with a greater improvement than the use of NSAIDs alone, but paracetamol alone did not induce any significant improvement. Placebo was not effective in reducing pain.
Full Access: Journal of Orthopedics

Age, epinephrine use, anaphylaxis impact quality of life in patients with food allergy
Older food allergy patients who have had anaphylaxis or needed epinephrine had lower quality of life than other patients, according to data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting. Overall, as age increased, food allergy quality of life got worse. The researchers found associations between greater allergic reaction severity and worse food allergy quality of life.
Full Access: Helio