THE COVID HEART—ONE YEAR AFTER SARS-COV-2 INFECTION, PATIENTS HAVE AN ARRAY OF INCREASED CARDIOVASCULAR RISKS
An analysis of data from nearly 154 000 US veterans with SARS-CoV-2 infection in Nature Medicine examined a comprehensive, prespecified set of cardiovascular outcomes among patients in the US Veterans Health Administration (VHA) system who survived the first 30 days of COVID-19. Patients with COVID-19 were at increased risk of a broad range of cardiovascular disorders including cerebrovascular disorders, dysrhythmias, ischemic and non–ischemic heart disease, pericarditis, myocarditis, heart failure, and thromboembolic disease.
Full Access: JAMA
GLOBAL BURDEN AND TRENDS OF SEXUALLY TRANSMITTED INFECTIONS FROM 1990 TO 2019: AN OBSERVATIONAL TREND STUDY
In this observational trend study, the age-standardized incidence rate of STIs showed a decreasing trend with an estimated annual percentage change of −0·04 (95% uncertainty interval [UI] −0·08 to 0·00) from 1990 to 2019. Although most countries showed a decrease in age-standardized rates of incidence and DALYs for STIs, the absolute incident cases and disability-adjusted life-years (DALYs) increased from 1990 to 2019. Therefore, STIs still represent a global public health challenge, especially in sub-Saharan Africa and Latin America, which warrants more attention and health prevention service.
Full Access: The Lancet
CHILDREN WITH SEVERE ASTHMA MAY BE MORE AT RISK FOR NSAID-EXACERBATED RESPIRATORY DISEASE
Children with severe asthma appeared more likely to experience NSAID-exacerbated respiratory disease, according to a study presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting. Children. Ibuprofen was the most common trigger of symptoms, at 18%, followed by aspirin and acetaminophen.
Full Access: Helio
PRESCRIBING NIRMATRELVIR–RITONAVIR: HOW TO RECOGNIZE AND MANAGE DRUG–DRUG INTERACTIONS
Nirmatrelvir–ritonavir (NMV/r) is increasingly available for use in high-risk patients with mild to moderate COVID-19. Safe prescribing of NMV/r requires full medication reconciliation, including over-the-counter medicines, herbals, and recreational drugs Interactions between NMV/r and comedications can be screened using specialized resources, such as the National Institutes of Health COVID-19 treatment guidelines or the University of Liverpool’s website on COVID-19 drug interactions.
Full Access: Annals of Internal Medicine