Urgent Updates | July 6

‘Impressive’ Results for Intranasal Ketamine in Chronic, Refractory Migraine

Half of the study participants who used IN ketamine for chronic, treatment- refractory migraine in a new retrospective cohort study reported it as “very effective” and over one third said it boosted their quality of life. Full Access: Medscape


Lupin Receives Approval from U.S. FDA for Tiotropium Dry Powder Inhaler Generic

United States Food and Drug Administration approved the New Drug Application for Tiotropium Bromide Inhalation Powder, 18 mcg/capsule, a generic equivalent of Spiriva® HandiHaler. Full Access: Lupin


Bacteremia Risk Low in Feverish Children and Young Adults with Sickle Cell Disease

A new study found the infectious bloodstream condition bacteremia was an unlikely diagnosis among children and young adults with sickle cell disease (SCD) who sought care in the emergency department (ED). However, investigators identified an increased likelihood of diagnosis if the patient had previous bacteremia infections or a history of central line placement. Full Access: HCP


Caring for Patients With Acute Respiratory Distress Syndrome

Summary of the 2023 ESICM Practice Guidelines: For nonintubated patients with acute hypoxemic respiratory failure not due to cardiogenic pulmonary edema or chronic lung disease – use high-flow nasal oxygen (HFNO) vs conventional oxygen therapy to reduce risk of intubation (strong recommendation; moderate level of evidence). Full Access: JAMA