Urgent Updates | April 27

Human Metapneumovirus, Or HMPV, Is Filling ICUs This Spring – A Pediatric Infectious Disease Specialist Explains This Little-Known Virus

Respiratory infections are the leading cause of death in children under 5 globally and a major reason for hospitalization of children in developed countries. The U.S. saw a spike in HMPV detections during the first few months of 2023. This trend is similar to the higher than normal cases of RSV, and influenza in the fall of 2022 and winter of 2023, likely related to decreased population immunity after two years of wearing face masks and social distancing. Full Access: Doximity


Universal Masking in Health Care Settings: A Pandemic Strategy Whose Time Has Come and Gone, For Now

Health care settings remain one of the last environments where widespread masking requirements continue despite the evolution of the pandemic and transition to endemicity.

The time has come to manage SARS-CoV-2 as we generally manage other endemic respiratory viruses in health care settings, which is through correct and consistent application of Standard Precautions and Transmission-Based Precautions (pathogen-specific). Full Access: Annals of Internal Medicine


Vaginal Swab vs Urine for Detection of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV): A Meta-Analysis

Researchers identified 28 eligible articles with 30 comparisons for CT, 16 comparisons for NG, and 9 comparisons for TV. Pooled sensitivity estimates for vaginal swabs and urine, respectively, were 94.1% and 86.9% for CT, 96.5% and 90.7% for NG, and 98.0% and 95.1% for TV (all P values <.001).  Evidence from this analysis supports the Centers for Disease Control and Prevention’s recommendation that vaginal swabs are the optimal sample type for women being tested for chlamydia, gonorrhea, and/or trichomoniasis. Full Access: Annals of Family Medicine


‘Bony’ Stroke: Bone Defects Can Cause Recurrent Stroke

the presence of structural bone and cartilage anomalies which cause mechanical stress to arteries supplying the brain — has been highlighted An unusual cause of ischemic stroke  “bony strokes” constitute a possible cause of recurrent ischemia in the same vascular territory as previous episodes. Full Access: Medscape