Urgent Updates | April 13

Sars-Cov-2 Crosses Placenta And Infects Brains Of Two Infants

Researchers have found for the first time that COVID infection has crossed the placenta and caused brain damage in two newborns. One of the infants died at 13 months and the other remained in hospice care at time of manuscript submission. Both infants tested negative for the virus at birth, but had significantly elevated SARS-CoV-2 antibodies in their blood, indicating that either antibodies crossed the placenta, or the virus crossed and the immune response was the baby’s. Full Access: Medscape

Likely Cause of Mysterious Hepatitis Outbreak in Kids Identified

More than 1000 children worldwide had been diagnosed with unexplained acute pediatric hepatitis as of August 2022. In the United States, there have been 358 cases, including 22 in which the child required a liver transplant and 13 in which the child died. Researchers found that simultaneous infection with adeno-associated virus type 2 (AAV2) and certain other viruses is associated with the outbreak of mysterious pediatric hepatitis cases worldwide. Full Access: Medscape

Paratracheal abscess by plant fungus Chondrostereum purpureum– first case report of human infection

Chondrostereum purpureum, is a plant fungus causing silver leaf disease of plants, particularly of the rose family. Here we report a case of paratracheal abscess caused by C. purpureum. This is a first of its kind of a case wherein this plant fungus caused disease in a human. Full Access: Science Direct

Association of Homelessness With Emergency Department Use Among Children in New York

Homelessness is a risk factor among children for acute health problems and barriers to ambulatory care. In this cross-sectional study researchers noted frequent ED use among New York children experiencing homelessness, particularly for mental health problems and conditions for which hospital encounters may be preventable through high-quality ambulatory care. These children’s substantially higher need for hospitalization, especially in ICUs, suggests a greater burden of severe illness as a principal driver of their ED use patterns. Full Access: JAMA