RISANKIZUMAB IN SEVERE ASTHMA — A PHASE 2A, PLACEBO-CONTROLLED TRIAL
PLACEBO BEAT RISANKIZUMAB IN ADULTS WITH SEVERE ASTHMA
The randomized, double-blind, 24-week, parallel group, multicenter trial assessed risankizumab efficacy and safety in 214 adults with severe persistent asthma. Placebo treatment was found to be superior to treatment with risankizumab with respect to time to first asthma worsening and annualized rate of asthma worsening for adults with severe persistent asthma in a phase 2a clinical trial.
Full Access: NJEM
BLADDER STIMULATION FOR CLEAN CATCH URINE COLLECTION. IMPROVED PARENT AND PROVIDER SATISFACTION
Previous studies have demonstrated the efficacy of fluid intake with suprapubic and lumbar paravertebral massage for clean catch urine collection in infants. Researchers investigated the acceptability and feasibility of integrating this bladder stimulation technique (BTS) into routine care in the pediatric emergency department. A total of 124 patient were recruited. The BST was successful in 38% and it was more likely to be successful in infants less than 90 days. Most providers reported that the BST was well tolerated by participants and providers felt that BST improved parental satisfaction.
Full Access: Pediatric Emergency Care
A CHANGE IN CLINICAL PRACTICE FOR AURAL FOREIGN BODIES – WHAT WE LEARNT FROM THE CORONAVIRUS DISEASE 2019 PANDEMIC
First study to specifically investigate the relationship between foreign body duration for up to three months from presentation and the risk of complications. A retrospective study of aural foreign body referrals over a six-month period. This case series data suggest that prolonged duration does not increase the incidence of complications.
Full Access: PMC
GINGER FOR MIGRAINE: A NEW REVIEW
Conducted by investigators at the National Institute of Mental Health and Neurosciences, Bangalore, India, the review showed ginger root can relieve migraine-related pain, nausea, and vomiting. However, the evidence does not support ginger’s use as a first-line therapy for acute migraine or for migraine prevention.
Full Access: Medscape